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Sensitivity to light. More precisely, on digital cameras ISO is how much the captured signal gets amplified.
In the film era, ISO really was the chemical sensitivity of the film. On digital, the sensor's physical sensitivity is fixed; the question is how much gain to apply during signal processing.
Which is why shooting at high ISO ≈ shooting at low ISO and pushing exposure in post (on ISO-invariant sensors).
Amplifying a signal also amplifies noise. In dark scenes the original signal is small, so the SNR (signal-to-noise ratio) gets noticeably worse when boosted.
The native sensitivity at which the sensor performs cleanest. Usually ISO 100 or 200.
Some cameras have two native sensitivities built into the sensor circuit. Above a threshold, the second circuit kicks in and noise drops again.
| Camera | Native ISO 1 | Native ISO 2 |
|---|---|---|
| Sony FX3 / FX6 | 800 | 12800 |
| Panasonic GH5s | 400 | 2500 |
| Canon C70 | 800 | 4000 |
→ On these cameras you get the counterintuitive result that ISO 12800 can be cleaner than ISO 6400. If your camera has dual native, lean into the second base.